Simon Fraser University announced on March 3, 2020 that researchers in its Brinkman Laboratory have collaborated with U.S. researchers to analyze a new drug that can kill a wide range of superbugs. (Simon Fraser University photo)

Human trials underway after B.C. researchers analyze effects of new ‘superbug-killing compound’

Brinkman Lab in Burnaby helped analyze effects of new drug after University of Cincinnati discovery

Researchers at Simon Fraser University’s Brinkman Lab in Burnaby participated in a landmark study that tests how a new drug can kill a range of superbugs – including some bacteria now resistant to all common antibiotics.

According to a March 3 release, researchers at the University of Cincinnati discovered two inexpensive chemicals work to kill disease-causing bacteria more effectively when combined.

The U.S. researchers combined the chemicals — ethylenediaminetetraacetic acid and acidified nitrite — to create the new drug known as AB569.

ALSO READ: B.C. widow sues health authority after ‘untreatable’ superbug killed husband

SFU researchers then used computers to analyze data from bacteria treated with the new drug. The results from the study indicated the drug can kill pathogens identified by the World Health Organization as urgently requiring new treatments, and posing the greatest threat to human health.

For example, the top three “priority pathogens” include Pseudomonas aeruginosa, a type of bacteria that can cause infections in the lungs, urinary tract, or blood that is known as the leading cause of morbidity in patients with cystic fibrosis.

Erin Gill, a PhD researcher at the University of British Columbia during the study and now at the Brinkman Lab, was involved in the analysis. She told Black Press Media by phone that it was inspiring to be part of “such a large, collaborative project.”

“It’s really important work to be able to contribute to the discovery of potentially novel drugs that can help to kill bacteria, because we’re running out of them,” Gill said.

The lab’s lead database developer Geoff Winsor agreed.

“We have a growing crisis with antibiotics becoming less and less effective, and treatments are failing,” Winsor said. “That’s why it’s important to test and develop new drugs and approaches to treat disease-causing bacteria that are highly resistant to existing antibiotics.”

The new drug is currently in the first phase of human trials that are being managed by Toronto-based biotechnology firm Arch Biopartners.

“I think they’re going to have some results from that soon,” Winsor said.

ALSO READ: SFU reviewing security measures after data breach exposes personal information

Correction: This story has been updated. The University of Cincinnati was responsible for testing the new AB569 drug, not the SFU Brinkman Lab.



karissa.gall@blackpress.ca

Like us on Facebook and follow us on Twitter

SFU

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

VIDEO: ‘Hands, washing hands’: Surrey teachers sing ‘Sweet Caroline’ with COVID-19 lesson

Staff at Fleetwood Park Secondary are featured in video posted to Youtube on Friday

Surrey’s JoJo Mason brings mom along for Saturday song during Diesel Bird Digital Music Festival

Online event March 28-29 to rally behind Canadian musicians hit by COVID-19 show cancellations

Delta council passes bylaw to fine people who don’t socially distance, respect closures

Not social distancing or obeying provincial orders in Delta could set you back hundreds of dollars

From lockdown in Italy to self-isolation in South Surrey

Like many returning citizens, Peninsula-raised James Bogart & Emily Schenk have a long journey ahead

Two workers at seniors’ homes in Surrey, Langley diagnosed with COVID-19

One is a staff member at Elim Village-The Harrison, at 9025 160th St., and the other is a health worker supporting and Chartwell Independent Living at Langley Gardens

Trudeau announces 75% wage subsidy for small businesses amid COVID-19

This is up from the previously announced 10 per cent wage subsidy

World update, 9:30 p.m. March 27: Positive news in Korea as U.S. hits 100,000 cases

The United States now has the most coronavirus cases of any country in the world

VIDEO: Penguins roam empty halls of Vancouver Aquarium

COVID-19 has forced the Vancouver Aquarium to close access to guests – leaving room for its residents

Significant snowfall forecast for Interior mountain passes

Allison Pass, the Okanagan Connector, Rogers Pass and Kootenay Pass could see 15 to 25 cm of snow

Kids get back to learning in B.C., online

Ministry of Education rolls out new tool for school

67 more B.C. COVID-19 cases, two more deaths in Vancouver region

Positive tests found in Surrey, Langley long-term care facilities

‘Now is not the time to bag that peak’: BCSAR manager discourages risky outdoor adventures

Call volumes are not going down, even as the COVID-19 pandemic persists

Food Banks BC already seeing surge in demand due to COVID-19 pandemic

Executive director Laura Lansink said they expect applications will keep increasing

Nanaimo couple caught aboard cruise ship with four dead and COVID-19 present

Four ‘older guests’ have died on Holland America’s Zaandam; cruise line confirms two COVID-19 cases

Most Read